The impact of rhinovirus infections in paediatric cardiac surgery a prospective cohort study
Completed
- Conditions
- common coldrhinovirus1001039410047438
- Registration Number
- NL-OMON46999
- Lead Sponsor
- Medische microbiologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 162
Inclusion Criteria
•Children (<12 year) with a congenital heart disease undergoing elective cardiac surgery
•Written informed consent by parents or guardian
Exclusion Criteria
•No informed consent from one of the parents (or the legal representative if applicable)
•Anaesthesiologist or cardiopulmonary surgeon postpones surgery based on routine hospital screening
•Emergency surgery
•Children not admitted to the intensive care unit after cardiac surgery
•Children undergoing a second cardiac operation during the same intensive care stay
•Children with duct-dependent physiology who remain prostaglandin-dependent after the heart operation
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary study parameter is PICU length of stay in per-operative<br /><br>rhinovirus-positive compared to rhinovirus-negative patients.</p><br>
- Secondary Outcome Measures
Name Time Method <p> Secondary outcome parameters are:<br /><br>• Duration of ventilatory support<br /><br>• Mechanical ventilation conditions (mean airway pressure, FiO2)<br /><br>• Antibiotic free days (alive at PICU discharge)<br /><br>• Need of inotropes (inotrope score)<br /><br>• Infection parameters<br /><br>• Hospital length of stay<br /><br>• Secondary infections</p><br>