The impact of rhinovirus infections in children undergoing cardiac surgery
Recruiting
- Conditions
- rhinovirus rhinoviruscardiac surgery hart operatierespiratory infection respiratoire infectiepost operative complications post operatieve complicaties
- Registration Number
- NL-OMON27376
- Lead Sponsor
- Drs. P.P. RoeleveldLeiden University Medical Center (LUMC)Department of paediatric Intensive Care Dr. J.J.C. de VriesLeiden University Medical Center (LUMC)Department of Medical Microbiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
•Children (<12 year) with a congenital heart disease undergoing elective cardiac surgery
•Written informed consent by parents or guardian
Exclusion Criteria
•No informed consent from one of the parents (or the legal representative if applicable)
•Anaesthesiologist or cardiopulmonary surgeon postpones surgery based on routine hospital screening
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary study parameter is post-operative PICU length of stay in rhinovirus positive compared to rhinovirus negative patients.
- Secondary Outcome Measures
Name Time Method Secondary outcome parameters are:<br /><br>•Duration of ventilatory support<br /><br>•Mechanical ventilation conditions (mean airway pressure, FiO2)<br /><br>•Antibiotic free days (alive at PICU discharge)<br /><br>•Need of inotropes (inotrope score)<br /><br>•Infection parameters<br /><br>•Hospital length of stay<br /><br>•Secondary infections<br /><br>