Cognitive behaviour therapy for co-morbid obsessive compulsive disorder in autism spectrum disorder

Completed

• Conditions: Disabling obsessions and compulsions in autism spectrum disorders; Mental and Behavioural Disorders; Obsessive-compulsive disorder

• Registration Number: ISRCTN87114880
• Lead Sponsor: Kings College London, Institute of Psychiatry (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-04-21
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Male and female, aged 14 years or older to a maximum of 65 years old
2. Verbal intelligence quotient (IQ) greater than 70
3. Diagnoses of ASD and co-morbid OCD

Exclusion Criteria

1. Current acute symptoms of psychosis
2. Uncontrolled seizure disorder or substance misuse disorder

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The following will be assessed at baseline (pre-treatment), end of treatment, 1, 3 and 6 months follow-up:<br>1. The Dimensional Yale Brown Obsessive Compulsive Scale (D-YBOCS) <br>2. The Obsessive Compulsive Inventory Revised (OCI-R) or Childrens Obsessive Compulsive Inventory (CH-OCI) <br>3. Beck Depression and Anxiety Scales or Spence Children's Anxiety Scale <br>4. Clinical Global Impressions Scale

Secondary Outcome Measures

Name	Time	Method
The following will be assessed at baseline (pre-treatment), end of treatment, 1, 3 and 6 months follow-up:<br>1. Liebowitz Social Anxiety Scale<br>2. Family Accommodation Scale<br>3. Work/School and Social adjustment scale<br>4. Parental CH-OCI