Efficacy of Split-Dose versus Single Dose of Ergocalciferol on Serum 25(OH)D in CAPD Patient: A Randomized Controlled Trial

Phase 3

Completed

• Conditions: CAPD patientinclusion criteria were CAPD patient with dialysis before enrolled for at least three months, aged > 18 years, who were diagnosed vitamin D deficiency and insufficiency, defined by vitam; Ergocalciferol, Vitamin D deficiency, Vitamin D insufficiency CAPD, Single dose, Split dose

• Registration Number: TCTR20200821005
• Lead Sponsor: one

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-12-12
• Study Start: 2020-08-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

inclusion criteria were CAPD patient with dialysis before enrolled for at least three months, aged > 18 years, who were diagnosed vitamin D deficiency and insufficiency, defined by vitamin D insufficiency was of 20â€29 ng/mL and deficiency was less than 20 ng/mL.

Exclusion Criteria

Subjects with history of liver diseases, patients known to have hypocalcaemia, hypercalcaemia or hyperparathyroidism, pregnant and lactating women, and history of urinary tract stone were excluded from the study. Discontinuation criteria included unwillingness to continue study, intolerable side-effects or allergy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
serum 25(OH)D concentrations 8 weeks Level of serum 25(OH)D concentrations

Secondary Outcome Measures

Name	Time	Method
Safety profile 4 and 8 weeks Level of calcium and phosphate concentrations