Omega-3 Fatty Acid Supplementation in Older Adults

Not Applicable

Withdrawn

• Conditions: Inflammation
• Interventions: Dietary Supplement: Omega-3 fatty acid; Dietary Supplement: Placebo

• Registration Number: NCT01666392
• Lead Sponsor: University of Memphis

Brief Summary

The purpose of this study to determine whether Fish oil (Omega-3 Fatty Acid) supplementation has an impact on inflammation and lean body mass in older adults. The investigators expect that Fish oil supplementation will reduce inflammation and prevent the loss of lean mass compared to placebo.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-08
• Study Start: 2012-08
• Study First Submitted: 2012-08-10
• Study First Submitted QC: 2012-08-15
• Study First Posted: 2012-08-16
• Last Update Submitted: 2012-10-08
• Last Update Posted: 2012-10-10
• Primary Completion: 2013-04
• Study Completion: 2013-04

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• 60 years of age or over

Exclusion Criteria

• Fish, seafood allergies, nut allergies, soy allergies
• Habitual (>1/week) fish or seafood consumption
• Current Omega-3 supplement use
• Gastrointestinal problems
• Current anti-inflammatory medication use
• Current anticoagulant medication use

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Fish oil (Omega-3 fatty acid)	Omega-3 fatty acid	2 capsules/day of ProOmega providing 650mg EPA and 450mg DHA
Soybean oil	Placebo	2 capsules/day

Primary Outcome Measures

Name	Time	Method
IL6	At baseline and at 3 month endpoint	Inflammatory cytokine
TNFα	At baseline and at 3 month endpoint	Inflammatory cytokine
C-Reactive protein	At baseline testing and at 3 month endpoint	Inflammatory marker

Secondary Outcome Measures

Name	Time	Method
Skeletal muscle mass/body composition	At baseline testing and at 3 month endpoint	The amount of skeletal muscle mass and fat mass and their ration will be determined.
Lower body muscular strength	At baseline and at 3 month endpoint	Measurement of maximum strength in the leg press exercise
Upper body muscular strength	At baseline and at 3 month endpoint	Measurement of maximum strength in the chest press exercise

Trial Locations

Locations (1)

Department of Health and Sport Sciences, The University of Memphis; 🇺🇸 Memphis, Tennessee, United States