Effect of Combined Fatty Acid Supplementation and Eccentric Exercise Training on Exercise Performance

Not Applicable

Completed

• Conditions: Exercise-induced Inflammation
• Interventions: Dietary Supplement: Fish Oil; Dietary Supplement: Placebo

• Registration Number: NCT03259412
• Lead Sponsor: Loughborough University

Brief Summary

The aim of the study is to determine whether fish oil (specifically omega-3 long chain polyunsaturated fatty acids \[EPA-DHA\]) supplementation can enhance eccentric resistance exercise performance when combined with a resistance exercise training study. The investigators aim to establish the potential mechanisms that might mediate performance changes at a cellular level.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-01
• Study First Submitted: 2017-08-04
• Study First Submitted QC: 2017-08-22
• Study First Posted: 2017-08-23
• Primary Completion: 2017-12-20
• Study Completion: 2017-12-20
• Status Verified: 2018-03
• Last Update Submitted: 2018-03-26
• Last Update Posted: 2018-03-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 18

Inclusion Criteria

• Males
• Healthy

Exclusion Criteria

• Resistance exercise training within the past 6 months
• Vitamin or fish oil supplementation over the past 6 months
• Habitual use of anti-inflammatory drugs
• History of heart disease
• History of coagulation/bleeding disorder
• History of metabolic disease
• Serious allergy
• Known to have blood-borne virus
• Females (Due to differences in cell membrane incorporation of Omega-3 between the sexes and the testing schedule being unable to fit in with menstrual cycle, altering the blood markers that are being measured)
• Currently no symptoms of general illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Fish Oil	Fish Oil	Fish oil 5.1g/ day - Premium Omega-3, Norwegian Pure-3, Oslo, Norway
Placebo	Placebo	Olive Oil 6g/ day - Premium Omega-3, Norwegian Pure-3, Oslo, Norway

Primary Outcome Measures

Name	Time	Method
Strength	Change from baseline strength at 11 weeks	Quadriceps and Hamstring strength using an isokinetic dynamometer
Leg power	Change from baseline strength at 11 weeks	Dynamic leg power assessed through jump height on force platform

Trial Locations

Locations (1)

Loughborough University; 🇬🇧 Leicester, United Kingdom