The effect of remifentanil on the reversal of established sunburn-induced hyperalgesia in human volunteers.
- Conditions
- This is a volunteer study in healthy volunteers. Pain research, reversal of hyperalgesia by IMP is studied
- Registration Number
- EUCTR2008-008475-34-AT
- Lead Sponsor
- Abteilung für Anaesthesie und Intensivmedizin, Medizinische Universität Wien
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
•Men or women, aged between 19 and 40 years
•Body mass index between 15th and 85th percentile
•Normal findings in the medical history and physical examination
•Drug free for 1 week prior to the study day
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Any of the following will exclude a subject from the study:
•Regular use of medication especially analgesics
•Abuse of alcoholic beverages, drug abuse
•History of asthma
•Participation in a clinical trial in the 2 weeks preceding the study
•Symptoms of a clinically relevant illness in the 2 weeks before the first study day
•Resting systolic blood pressure >135 mmHg or diastolic blood pressure >85 mmHg
•Acute skin diseases like sunburn or skin lesions on the relevant areas and UV sensitive skin conditions, like Xeroderma pigmentosa
•Pregnancy or breast feeding
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method