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The Effect of High-dose Remifentanil on the Reversal of Neuropathic Pain in Postherpetic Patients - RemiHighDose PHZ

Phase 1
Conditions
Post herpetic hyperalgesia
Registration Number
EUCTR2010-020042-94-AT
Lead Sponsor
Medizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
21
Inclusion Criteria

•Patients suffering from PHN.
•Pain = 4 out of 10 in numeric rating scale (NRS)
•Female and male patients above the age of 18
•Ability to understand/write/read german

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

•Any of the following will exclude a subject from the study:
•Zoster affecting trigeminal-, opticus region
•Any somatic pain which is stronger than the neuropathic pain
•Severe progressive disease
•Acute cardiac decompensation
•Known cardiac valve dysfunction
•Known pulmonary hypertension
•Cardiac conduction disturbance
•Active herpetic lesion
•Analgesic or antitussive opioid therapy
•Bronchial asthmal
•Known chronic obstructive pulmonary disease (COPD) >GOLD II
•Severe psychiatric condition
•Abuse of alcoholic beverages, drug abuse
•Negative neuropathic symptoms
•Pregnancy or breast feeding
•Participation in a clinical trial in the 2 weeks preceding the study
•Allergy against any medication used in the study protocol

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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