Dexmedetomidine causes change in vital parameters after intubatio
Phase 1
- Conditions
- Health Condition 1: null- ASA Grade I & II patients
- Registration Number
- CTRI/2018/04/013000
- Lead Sponsor
- ESIPGIMSR and Model hospital andheri
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient posted for surgery under general anesthesia.
Patients belonging to ASA class I & II.
Exclusion Criteria
1 Patients with hypertension, cardiac, respiratory, renal, hepatic &
cerebral diseases
2. Patients with difficult airway and obese patients.
3. Patients with endocrinal diseases like hyperthyroidism, hypothyroidism
and diabetes mellitus.
4. Pregnant patient
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To study the efficacy of 1μg/kg dexmedetomidine intravenous given in 100 <br/ ><br>ml NS over 10 minutes before induction to obtund the pressor response of <br/ ><br>laryngoscopy and tracheal intubation with respect to- Heart rate, systolic blood <br/ ><br>pressure, diastolic blood pressure, Mean arterial pressure.Timepoint: Baseline, at 5 and 10 mins during drug infusion, after induction, at and 5,10 mins after intubation
- Secondary Outcome Measures
Name Time Method To study any adverse effects associated, such as perioperative <br/ ><br>hypotension, bradycardia.Timepoint: Baseline, at 5 and 10 mins during drug infusion, after induction, at and 5,10 mins after intubation