Priorities Aligned Deprescribing for Persons Living With Dementia and Their Caregiver
- Conditions
- Dementia
- Interventions
- Behavioral: Usual careBehavioral: PPC
- Registration Number
- NCT05970315
- Brief Summary
The purpose of this study is to compare patient priorities care (PPC) and usual care (UC) patients to identify differences in post-encounter medication changes, treatment burden (TBQ), and shared decision making in Older Patient Assessment of Chronic Illness Care (OPACIC), to understand PPC participant's sense-making and communication approaches related to deprescribing decisions in relation to the identified health priorities and to identify and categorize adverse drug withdrawal events (ADWEs)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 50
- Dementia listed as an active problem in the medical record, including Alzheimer's disease, vascular dementia, frontotemporal dementia, Parkinson's dementia, Lewy body disease.
- The functional assessment staging tool (FAST) score of 5 or lower (This will be established by the patient's clinician).
- 2 or more additional chronic conditions
- Takes 5 or more regular medications and
- A caregiver present during visits. Caregivers may include family members or unrelated caregivers and will be identified through chart review and confirmed by clinician, patient, and surrogate decision maker if necessary. Identified caregivers must be involved in decisions and care of People living with dementia (PLWD) and routinely attend clinic visits with patient
- FAST score of 6 or more (This will be established by the patient's clinician).
- Significant hearing, vision, or advanced cognitive impairment that limits ability to participate in PPC encounters,
- Caregiver is unwilling or able to participate in visits, or
- Deemed ineligible by their Primary care physician (PCP)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Usual Care Usual care - PPC PPC -
- Primary Outcome Measures
Name Time Method Number, likelihood, and severity of adverse drug reactions (ADRs) as assessed by the Naranjo scale 3 months Naranjo scale is a 10 item questionnaire.Total scores range from -4 to +13; the reaction is considered definite if the score is 9 or higher, probable if 5 to 8, possible if 1 to 4, and doubtful if 0 or less.
Change in patient reported treatment burden as assessed by the Treatment Burden Questionnaire (TBQ) Baseline, 3 month This is a 15 item questionnaire and each is scored from 0(not a problem) to 10(big problem) for a maximum score of 150, higher number indicating more burden
Number of medication changes Baseline, 3 month Type of medication changes Baseline, 3 month Number, likelihood, and severity of adverse drug withdrawal events (ADWEs) as assessed by the Naranjo scale 3 months Naranjo scale is a 10 item questionnaire.Total scores range from -4 to +13; the reaction is considered definite if the score is 9 or higher, probable if 5 to 8, possible if 1 to 4, and doubtful if 0 or less.
- Secondary Outcome Measures
Name Time Method Patient perceived chronic disease care as assessed by the Older Patient Assessment of Chronic Illness Care (OPACIC) score Baseline, 3 months This is a 10 item questionnaire and each is scored from 1(almost never) to 5(almost always),for a maximum score of 50 ,higher scores indicate better perceived chronic disease care
Trial Locations
- Locations (1)
The University of Texas Health Science Center at Houston
🇺🇸Houston, Texas, United States