Comparing the effect of albumin and crystalloid serum as resuscitation fluid in survival of patients with severe sepsis shock
- Conditions
- Septic shock.Septic shock
- Registration Number
- IRCT2016040316473N5
- Lead Sponsor
- Vice chancellor for research, Tabriz University Of Medical Sciences.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
age between 12 to 75 years old; existence of at least two symptoms of SIRS syndrome (body temperature above 38 or below 36 ° C.; respiratory rate above 20 or PCO2 less than 32 or need for mechanical ventilation; heart rate more than 90, leukocytosis above 12,000 or leukopenia less than 4000 or band cells in peripheral blood smear); existence of a focal infection based on positive culture or existence of an obvious infected area such as peritonitis or pneumonia; need to resuscitation with fluid (tachycardia; systolic blood pressure less than 100 mm Hg or mean arterial pressure less than 75 mm Hg; urine volume less than 0.5 cc/kg/hr; need for vasopressor to maintain blood pressure; central venous pressure (CVP) less than 10 mm Hg).
Exclusion criteria: brain death patients; patients undergoing plasmapheresis; contraindications of albumin infusion; heart failure or pulmonary failure or renal failure; transplant patients; patients with burns; heart surgery at 3 recent months.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survival of patients. Timepoint: Daily for 28 days. Method of measurement: clinical examination.
- Secondary Outcome Measures
Name Time Method Renal failure. Timepoint: Daily for 28 days. Method of measurement: Creatinine level.