Comparison of albumin-normal saline and albumin-gelatin injection on early outcome after liver transplant surgery

Phase 2

Recruiting

• Conditions: Liver transplant status; Z94.4; iver transplant.

• Registration Number: IRCT20141009019470N88
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 October 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

The final stage of liver disease
Age over 18 years
Patients candidate for liver transplantation from brain death donors

Exclusion Criteria

Liver recipients from live donors
Patients undergoing redo transplantation
History of upper abdominal surgery
A history of allergies to colloids
History of kidney dysfunction confirmed by laboratory and ultrasound tests

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Glomerular filtration rate. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Cochcroft and Gault formula.;Serum creatinine level. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.;Blood Urea Nitrogen. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.;Liver Function Tests: (AST, ALT, ALKP, INR, Bilirubin), Albumin. Timepoint: On the first day, second day, third day, fifth day and the last day of hospitalization. Method of measurement: Venous blood sample.

Secondary Outcome Measures

Name	Time	Method
ICU stay. Timepoint: At arrival time until the discharge from intensive care unit. Method of measurement: Observation.;Time interval between completion of operation and extubation. Timepoint: Between completion of operation to extubation. Method of measurement: Observation.;Hospital Stay. Timepoint: Hospital discharge time. Method of measurement: Observation.