A clinical trial study-Use of oral colchicine in treatment of patients with oral submucous fibrosis
Phase 3
- Registration Number
- CTRI/2020/07/026322
- Lead Sponsor
- DrArchana Chandrakant Marlapalle
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Grade III patient â?? moderately advanced cases of OSMF (15 â?? 25mm)
No other curative agent used
Exclusion Criteria
Medically compromised condition
Pregnant and breastfeeding females
Trismus due to any other reason such as pericoronitis, dental abscess
Patients taking drugs that are CYP3A4&P-gp inhibitors like
erythromycin, clarithromycin, fluconazole, verapamil, grapefruit
juice and HIV drugs
Allergy to prednisolone and colchicine
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increase in interincisal mouthopeningTimepoint: After 9 MONTH OF INTERVENTIO
- Secondary Outcome Measures
Name Time Method Efficacy of drugTimepoint: 9 months