Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia

Not Applicable

• Conditions: Schizophrenia
• Interventions: Device: Magnetic Resonance Imaging; Other: EVALUATION NEUROPSYCHOLOGICAL

• Registration Number: NCT01295411
• Lead Sponsor: Assistance Publique Hopitaux De Marseille

Brief Summary

The aim of the investigators analysis is to identify the neural correlates of quality of life scores in schizophrenia. For this, the investigators will constitute group of patients according to their quality of life scores and the investigators will analyze their differences in patterns of brain structures and activations.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-01
• Study First Submitted: 2011-02-09
• Study First Submitted QC: 2011-02-11
• Study First Posted: 2011-02-14
• Primary Completion: 2015-01
• Status Verified: 2015-04
• Last Update Submitted: 2015-04-27
• Last Update Posted: 2015-04-28
• Study Completion: 2015-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria (American Psychiatric Association(APA), 1994),
• age over 18 years,
• informed consent to participate in the studies
• French as native language

Exclusion Criteria

• diagnosis other than schizophrenia on Axis I of DSM-IV,
• decompensated organic disease and mental retardation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
schizophrenia PATIENTS	EVALUATION NEUROPSYCHOLOGICAL	-
schizophrenia PATIENTS	Magnetic Resonance Imaging	-

Primary Outcome Measures

Name	Time	Method
to study the relationships between quality of life and the morphologic, structural and functional substrates in schizophrenia	36 months

Secondary Outcome Measures

Name	Time	Method
to determine whether quality of life is correlated with brain modifications using functional Magnetic Resonance Imaging	36 months

Trial Locations

Locations (1)

Assistance Publique Hopitaux de Marseille; 🇫🇷 Marseille, France