A comparison of twenty-four-hour blood pressure control between candesartan and other ARBs estimated by the ambulatory blood pressure monitoring
Not Applicable
- Conditions
- essential hypertension
- Registration Number
- JPRN-UMIN000003684
- Lead Sponsor
- Department of Integrated Medicine, Ehime University Graduate Schoolof Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1. secondary hypertension 2. systolic blood pressure >160 mmHg and or diastolic blood pressure > 100 mmHg 3. malignant hypertension 4. history of stroke, myocardial infarction and other cardiovascular disease that needed hospitalization within recent 6 months. 5. atrial fibrillation 6. patients with fundal hemorrhage, exudation or papilledema due to hypertensive retinopathy 7. liver dysfunction(the levels of AST or ALT reached 250% of their upper normal limit.) 8. Renal dysfunction (serum creatinine > 2.0 mg/dl) 9. hyperkalemia (serum K > 5.5 mEq/l) 10. pregnant or nursing women 11. patients who are not recommended for participation in this study by physician in charge with medical reasons.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The difference of mean nocturnal blood pressure between candesartan and other angiotensin 2 receptor blockers.
- Secondary Outcome Measures
Name Time Method The difference of mean 24-hour blood pressure between candesartan and other angiotensin 2 receptor blockers. The difference of mean morning blood pressure between candesartan and other angiotensin 2 receptor blockers. Percentage of the patient who achieved the target of 24-hour blood pressure in Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2009).