Effect of a Probiotic, Lactobacillus FARCIMINIS, in Diarrhea Predominant IBS

Assistance Publique - Hôpitaux de Paris1 site in 1 country60 target enrollmentOctober 2007

ConditionsIrritable Bowel Syndrome

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Irritable Bowel Syndrome
Sponsor: Assistance Publique - Hôpitaux de Paris
Enrollment: 60
Locations: 1
Primary Endpoint: Overall subject's assessment
Status: Completed
Last Updated: 15 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Probiotics may improve symptoms in IBS patients. The aim of this study is to test the efficacy of Lactobacillus FARCIMINIS in diarrhea predominant IBS patients according to Rome III criteria.

Detailed Description

The aim of this study is to test the efficacy of Lactobacillus FARCIMINIS in diarrhea predominant IBS patients according to Rome III criteria.

Registry

clinicaltrials.gov

Start Date

October 2007

End Date

June 2010

Last Updated

15 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Assistance Publique - Hôpitaux de Paris

Eligibility Criteria

Inclusion Criteria

•Diarrhea predominant IBS
•Less than 5-year duration
•Pain intensity between 2 and 7 on VAS

Exclusion Criteria

•Celiac disease
•Antibiotic treatment within the 1-month period preceding inclusion
•Digestive organic disease
•Any severe non digestive organic disease

Outcomes

Primary Outcomes

Overall subject's assessment

Time Frame: 4 weeks

Secondary Outcomes

Decrease in abdominal pain, stool form and consistency, modifications in intestinal permeability, modification in fecal serine protease activity, modifications in interleukin seric concentrations(4 weeks)