Evaluation of the Effects of Lactol Probiotic in Comparison With Placebo on Symptoms of Irritable Bowel Syndrome
Overview
- Phase
- Phase 2
- Intervention
- Lactol
- Conditions
- Irritable Bowel Syndrome
- Sponsor
- Islamic Azad University, Najafabad Branch
- Enrollment
- 82
- Locations
- 1
- Primary Endpoint
- Abdominal pain
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
Some evidences have shown that probiotics are effective in the treatment of irritable bowel syndrome. Because few evidences are available in our population, we investigated if probiotics are effective in our patients as well. We hypothesize that the probiotic Lactol which contains Lactobacillus Sporogenes reduces the symptoms of irritable bowel syndrome.
Investigators
Mozhdeh Zahiri
Dr.
Islamic Azad University, Najafabad Branch
Eligibility Criteria
Inclusion Criteria
- •age between 18 and 65
- •diagnosis of IBS based on the Rome III criteria
- •willingness to participate
Exclusion Criteria
- •receiving other probiotics compound during the study
- •receiving antibiotics during the study
Arms & Interventions
Lactol
Intervention: Lactol
Placebo
Intervention: Placebo
Outcomes
Primary Outcomes
Abdominal pain
Time Frame: Up to 3 months
Abdominal pain was assessed by Rome III questionnaire at baseline and then after 3 months.
Diarrhea
Time Frame: Up to 3 months
Diarrhea was assessed by Rome III questionnaire at baseline and then after 3 months.
Constipation
Time Frame: Up to 3 months
Constipation was assessed by Rome III questionnaire at baseline and then after 3 months.