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临床试验/CTRI/2022/12/048536
CTRI/2022/12/048536尚未招募未知

euroimaging and genetic correlates of motor cortical neuroplasticity and implicit motor learning in patients with schizophrenia, major depressive disorder, and healthy controls: A transdiagnostic study

Ashok Jammigumpula0 个研究点目标入组 0 人开始时间: 待定最近更新:

试验速览

阶段
未知
状态
尚未招募
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

入选标准

  • Schizophrenia
  • Schizophrenia (according to DSM 5) with persisting symptoms
  • Score of >=4 on one or more of the items of BPRS
  • 4 (conceptual disorganization)
  • 11 (suspiciousness)
  • 12 (hallucinatory behaviour)
  • 15 (unusual thought content)
  • A score of >=12 on all the above items combined
  • Right-handed in accordance with the Edinburgh Handedness Inventory
  • Speak either Kannada or English
  • Written informed consent
  • Major Depressive Disorder (according to DSM 5) with persisting symptoms
  • HAMD-17 score >=18
  • Right-handed in accordance to the Edinburgh Handedness Inventory
  • Speak either Kannada or English
  • Written informed consent
  • Healthy Controls
  • Matched for age, gender and education
  • Right-handed in accordance to the Edinburgh Handedness Inventory
  • Speak either Kannada or English
  • Written informed consent

排除标准

  • Schizophrenia
  • Any history of other major psychiatric disorders
  • Neurological disorders associated with movement impairments
  • SUD in the last six months (except nicotine)
  • Any contraindication to HD-tDCS or TMS
  • Any history of other major psychiatric disorders
  • Neurological disorders associated with movement impairments
  • Bipolar depression
  • Psychotic disorder or symptoms
  • SUD in the last six months (except nicotine)
  • Any contraindication to HD-tDCS or TMS
  • Healthy Controls
  • Any history of major psychiatric disorders
  • SUD in the last six months (except nicotine)
  • Neurological disorders associated with movement impairments
  • Major psychiatric illnesses in first-degree relatives
  • Any contraindication to HD-tDCS or TMS

研究者

发起方
Ashok Jammigumpula

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