rine prothrombin fragments (F1+2) as a diagnostic tool for arterial and venous thrombosis

• Conditions: 10011082; 10003216; bloedstolling, veneuze trombo embolien; arterial and venous thrombosus; deep vein thrombosus; myocardial infarction; pulmonary embolism; thrombosus

• Registration Number: NL-OMON34836
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

Males and females, aged 18 years and older with an objectively confirmed venous thrombo-embolism, either DVT or PE (by means of ultrasonography, computerized tomography or ventilation perfusion scanning) and an objectively confirmed diagnosis of
myocardial infarction (by means of elevated cardiac enzymes or abnormal elecocardiogram.

Exclusion Criteria

Since this is a pilot study, there are no exclusion criteria.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Urine F1+2 levels </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Increased levels of urine F1+2 coincide with increased plasma levels of ddimer<br /><br>and F1+2 in case of VTE and troponine T, CKMB, d-dimer and F1+2 in plasma<br /><br>samples in patients with MI.</p><br>