Inter-individual variation in susceptibility to colorectal neoplasia: the interaction between diet, DNA damage markers and genetic polymorphisms.
Completed
- Conditions
- Colorectal cancerCancerMalignant neoplasm of other and ill-defined digestive organs
- Registration Number
- ISRCTN41928225
- Lead Sponsor
- HS R&D Regional Programme Register - Department of Health (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 0
Inclusion Criteria
All people (male and female) randomised to the screening arm of the Flexi-scope Trial will be invited to participate in this study. General practioners are initially approached and if they agree to take part in the Flexi-Scope Trial all patients aged 55-64 are contacted by questionnaire to declare interest in that study.
Exclusion Criteria
1. People unable to provide informed consent.
2. People with a history of colorectal cancer, adenomatous polyps or inflammatory bowel disease.
3. People with severe or terminal disease, with life expectancy of less than 5 years.
4. People with a recent history of sigmoidoscopy or colonoscopy (within 2 years).
5. People unfit for flexible sigmoidoscopy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method