TO COMPARE HEMODYNAMIC PARAMETER AND POST-OPERATIVE ANALGESIA OF KETAMINE AND MAGNESIUM SULPHATE IN PRE-EMPTIVE DOSES IN PATIENT UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY UNDER GENERAL ANAESTHESIA
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/12/048059
- Lead Sponsor
- SIKKIM MANIPAL INSTITUTE OF MEDICAL SCIENCES
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. American society of Anaesthesiology score [ASA] I and 2
2. Age between 18 years and 65 years
3. Surgery lasting between 60 to 90 mins
4. Laparoscopic cholecystectomy using four ports
Exclusion Criteria
Patient refusal
2. Any systemic co-morbidity including uncontrolled hypertension and
diabetes, Heart block, renal impairment (serum creatinine greater than
2mg/dl, hepatic impairment (trans-aminases greater than double the
normal values), psychiatric disorders like Schizophrenia and Mania
3. Patient on any addictive drug or allergic to any drug used in the trial
4. Pregnant patient and lactating mothers
5. Glaucoma, raised intracranial pressure
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method KETAMINE IS SUPERIOR TO MAGNESIUM SULPHATE AS IT PROVIDE BETTER INTRA-OPERATIVE AND POST-OPERATIVE ANALGESIA AND IT DELAYS THE TIME FOR THE FIRST RESCUE ANALGESIA REQUEST.Timepoint: Patient wll be monitored for post-operative analgesia for 24 hrs.
- Secondary Outcome Measures
Name Time Method changes in hemodynamic parameterTimepoint: hemodynamic parameters will be monitored for 60 mins