Cardiac sympathetic nervous system function and activity as a predictor for appropriate ICD therapy in patients with chronic heart failure
Completed
- Conditions
- heart failure and fatal arrhytmiassudden cardiac death10007521
- Registration Number
- NL-OMON33730
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 300
Inclusion Criteria
*Left ventricular dysfunction (LVEF *35%) due to prior MI (at least 40 days post MI)
*Left ventricular dysfunction (LVEF *35%) due to non-ischemic heart disease
*NYHA functional class II and III
*Receiving chronic optimal medical therapy
*Reasonable expectation of survival with a good functional status of more than 1 year
Exclusion Criteria
*pregnancy
*Left ventricular ejection fraction >35%
*NYHA functional class I and IV
*Not receiving chronic optimal medical therapy
*Expected survival less than 1 year
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary endpoint of the trial will be appropriate ICD discharge or<br /><br>anti-tachycardia pacing. </p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>