Pre-emptive Analgesia Using Nebulized Ketamine Versus Nebulized Dexmedetomidine in Endoscopic Nasal Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 105
- 试验地点
- 1
- 主要终点
- This study aims to assess the efficacy of nebulized dexmedetomidine vs nebulized ketamine to achieve good postoperative pain management in patients undergoing endoscopic nasal surgeries.
研究概览
简要总结
this study aims to compare the efficacy of pre-emptive nebulized ketamine versus nebulized dexmedetomidine for post operative pain relief in endoscopic nasal surgery
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients between the ages of 20 and 60,
- •both sexes,
- •American Society of Anesthesiologists physical status I to II
- •BMI ≥18≤30 kg/m²
排除标准
- •Patient refusal.
- •patients with advanced respiratory, renal, hepatic, neurological, or psychiatric disease, pregnant or nursing women.
- •patients with a history of allergies to any study drugs.
- •patients who had used central nervous system depressants or analgesics within the previous 24 hours.
- •patients with hypertension, hypotension, or bradycardia.
研究组 & 干预措施
group D : will receive dexmedetomidine
Patients will receive nebulized dexmedetomidine 50 μg (0.5 ml +normal saline 0.9% up to 3 ml) 15 minutes prior to the onset of surgery.
干预措施: Dexmedetomidine (Drug)
group K : will receive ketamine
patients will receive nebulized ketamine 50 mg (1 ml + normal saline 0.9%up to 3 ml) 15 minutes prior to the onset of surgery.
干预措施: Ketamine (Drug)
group C: will receive .9% saline
Patients will receive nebulized normal saline 0.9% (3 ml) 15 minutes prior to the onset of surgery.
干预措施: 0.9%sodium chloride (Drug)
结局指标
主要结局
This study aims to assess the efficacy of nebulized dexmedetomidine vs nebulized ketamine to achieve good postoperative pain management in patients undergoing endoscopic nasal surgeries.
时间窗: 24 hours after operation
post operative pain management by VAS
次要结局
未报告次要终点
研究者
Ahmed Thabet Abdelhameed
Resident , Anesthesia , Surgical Icu , Pain management Faculty of Medicine Sohag university
Sohag University