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临床试验/NCT05352204
NCT05352204已完成不适用

The Guiding Value of Tumor Micronecrosis for Using Postoperative Transcatheter Arterial Chemoembolization in Patients With Hepatocellular Carcinomas

Zhejiang University2 个研究点 分布在 1 个国家目标入组 900 人开始时间: 2020年4月30日最近更新:
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适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
900
试验地点
2
主要终点
overall survival
研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Micronecrosis is a novel pathological feature of hepatocellular carcinoma (HCC). This study was aimed at evaluating the effect of tumor micronecrosis on postoperative transcatheter arterial chemoembolization (TACE) in patients with hepatocellular carcinomas, and further exploring the value of micronecrosis for guiding TACE in HCC management.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者
否

入选标准

  • •(1) pathologically confirmed HCC (2) achievement of R0 resection.

排除标准

  • •(1) simultaneous presence of other tumors ; (2) receipt of preoperative anti-tumoral treatments; (3) concurrent treatment with other antitumoral therapies in combination with TACE; (4) tumor necrosis that could be observed by gross examination; (5) a lack of necessary preoperative laboratory test results.

结局指标

主要结局

overall survival

时间窗: after liver resection until June 1, 2020

the number of months from the date of surgery to the date of the last follow-up visit or time of death.

次要结局

  • disease-free survival(after liver resection until June 1, 2020)

研究者

发起方
Zhejiang University
申办方类型
Other
责任方
Principal Investigator
主要研究者

TingBo Liang

FACS

Zhejiang University

研究点 (2)

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