NL-OMON44725
Completed
Not Applicable
Microbiome and lower respiratory tract infections in children - Microbiome and LRTI
Spaarne Ziekenhuis0 sites975 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- bronchitis or pneumonia
- Sponsor
- Spaarne Ziekenhuis
- Enrollment
- 975
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All groups:
- •Children \* 4 weeks and \* 5 years and;Non\-severe LRTI group:
- •Hospitalized for a LRTI at a general pediatric ward. ;Severe LRTI group:
- •Hospitalized at the intensive care ward for a severe LRTI;Control group must fulfil all the following criteria:
- •1\. Children matched with LRTI case for age (in years). In addition children \< 1 year will be matched for months in two categories: 4 weeks \- 6 months or 6 months \- 1 year.
- •2\. Matched with hospital admission date of LRTI case \+ maximal two weeks.
- •3\. Matched for gender.
- •4\. No fever and/or respiratory tract infection (except rhinitis) in the previous four weeks.
- •5\. No antibiotics in the previous 3 months.
Exclusion Criteria
- •\- Severe concomitant disease (severe congenital heart disease, bronchopulmonary dysplasia, prematurity \<32 weeks, cystic fibrosis, sickle cell disease, congenital or acquired immunodeficiency disorders, cardiovascular disease, neuromuscular disorders, oncology patients or major congenital anomalies) and/or
- •\- Nosocomial infection and/or
- •\- Language barrier
Outcomes
Primary Outcomes
Not specified
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