CTRI/2024/11/076971
Not yet recruiting
Phase 2/3
A comparative evaluation of 5 percent Moringa Oleifera mouthwash and 0.2 percent Chlorhexidine Gluconate mouthwash. A randomized control clinical trial.
Dr Kanika Singhal1 site in 1 country30 target enrollmentStarted: December 10, 2024Last updated:
Overview
- Phase
- Phase 2/3
- Status
- Not yet recruiting
- Sponsor
- Dr Kanika Singhal
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Plaque index- Silness and Loe
Overview
Brief Summary
The current gold standard in mouthwashes is Chlorhexidine Gluconate, but it still has some disadvantages like staining teeth and taste alterations. So, the study here aims at finding an alternative to Chlorhexidine mouthwash which can work in a similar manner. Also, the study uses a plant extract, i.e., Moringa oleifera leaf powder, which is already available commercially for various uses. The mouthwash will be prepared in the lab and then used.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 45.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Systemically healthy, minimum 20 functional teeth, GI score less than or equal to 2.
Exclusion Criteria
- •Malaliggned teeth, removabe or fixed partial denture, orthodontic appliance, tobacco chewer, smoker.
Outcomes
Primary Outcomes
Plaque index- Silness and Loe
Time Frame: 6th and 24th day
Secondary Outcomes
- Gingival Index- Loe and Silness(6th and 24th day)
- Bleeding Index- Muhlemann(6th and 24th day)
Investigators
Dr Kanika Singhal
RUHS COLLEGE OF DENTAL SCIENCES, JAIPUR
Study Sites (1)
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