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Clinical Trials/CTRI/2024/11/076971
CTRI/2024/11/076971
Not yet recruiting
Phase 2/3

A comparative evaluation of 5 percent Moringa Oleifera mouthwash and 0.2 percent Chlorhexidine Gluconate mouthwash. A randomized control clinical trial.

Dr Kanika Singhal1 site in 1 country30 target enrollmentStarted: December 10, 2024Last updated:

Overview

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
Dr Kanika Singhal
Enrollment
30
Locations
1
Primary Endpoint
Plaque index- Silness and Loe

Overview

Brief Summary

The current gold standard in mouthwashes is Chlorhexidine Gluconate, but it still has some disadvantages like staining teeth and taste alterations. So, the study here aims at finding an alternative to Chlorhexidine mouthwash which can work in a similar manner. Also, the study uses a plant extract, i.e., Moringa oleifera leaf powder, which is already available commercially for various uses. The mouthwash will be prepared in the lab and then used.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 45.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Systemically healthy, minimum 20 functional teeth, GI score less than or equal to 2.

Exclusion Criteria

  • Malaliggned teeth, removabe or fixed partial denture, orthodontic appliance, tobacco chewer, smoker.

Outcomes

Primary Outcomes

Plaque index- Silness and Loe

Time Frame: 6th and 24th day

Secondary Outcomes

  • Gingival Index- Loe and Silness(6th and 24th day)
  • Bleeding Index- Muhlemann(6th and 24th day)

Investigators

Sponsor
Dr Kanika Singhal
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Dr Kanika Singhal

RUHS COLLEGE OF DENTAL SCIENCES, JAIPUR

Study Sites (1)

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