CTRI/2025/08/092528
Completed
Phase 3
Efficacy of pomegranate mouth rinse compared to chlorhexidine on plaque accumulation, gingival inflammation and salivary bacterial count -A Randomised Controlled Trial.
Dr Anoop S1 site in 1 country70 target enrollmentStarted: August 18, 2025Last updated:
Overview
- Phase
- Phase 3
- Status
- Completed
- Sponsor
- Dr Anoop S
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- plaque index (Silness and Loe)
Overview
Brief Summary
To determine the effect of herbal mouthwash prepared from pomegranate peel compared to chlorhexidine mouthwash in reducing plaque accumulation, gingival health, and salivary bacterial count.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 50.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Individuals with a gingival index score ≥1 and a plaque index score ≥1, a minimum of 12 gradable teeth, no requirement for emergency oral prophylaxis, and willing to give written informed consent to participate in the study and comply with the study visits.
Exclusion Criteria
- •Individuals with history of steroid or antimicrobial therapy in the last 3 months Individuals with any medical condition Smokers Adults with periodontitis Allergic to chlorhexidine and pomegranate.
Outcomes
Primary Outcomes
plaque index (Silness and Loe)
Time Frame: baseline, 5days, 21 days
gingival index (Loe and Silness)
Time Frame: baseline, 5days, 21 days
salivary bacterial colony forming units
Time Frame: baseline, 5days, 21 days
Secondary Outcomes
No secondary outcomes reported
Investigators
Anoop S
Government Dental College, Thiruvananthapuram
Study Sites (1)
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