Diabetes-Specific Nutritional Formulas Versus Oatmeal

Not Applicable

Completed

• Conditions: Type 2 Diabetes Mellitus; Obesity
• Interventions: Dietary Supplement: Oatmeal breakfast; Dietary Supplement: Glucerna formula; Dietary Supplement: Ultra Glucose Control formula

• Registration Number: NCT02691481
• Lead Sponsor: Joslin Diabetes Center

Brief Summary

Diabetes-specific nutritional formulas (DSNFs) are frequently used as part of medical nutrition therapy for patients with type 2 diabetes in order to improve glycemic control and enhance weight reduction. The mechanism through which DSNFs improve postprandial (PP) plasma glucose is not yet known.

The aim of this study is to compare the effects of 2 DSNFs versus oatmeal on PP plasma glucose, serum insulin and serum active glucagon-like peptide-1 (GLP-1), serum free fatty acids (FFA) and serum triglycerides (TG).

Detailed Description

Not available

Study Timeline

• Study Start: 2014-05
• Primary Completion: 2014-09
• Study Completion: 2014-10
• Status Verified: 2016-02
• Study First Submitted: 2016-02-22
• Study First Submitted QC: 2016-02-22
• Last Update Submitted: 2016-02-22
• Study First Posted: 2016-02-25
• Last Update Posted: 2016-02-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Patients with type 2 diabetes treated with oral diabetes medications

Exclusion Criteria

• Type 1 diabetes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Ultra Glucose Control formula	Oatmeal breakfast	consuming 200 kcal of Ultra Glucose Control shake for breakfast
Glucerna formula	Oatmeal breakfast	consuming 200 kcal of Glucerna shake for breakfast
Ultra Glucose Control formula	Ultra Glucose Control formula	consuming 200 kcal of Ultra Glucose Control shake for breakfast
Glucerna formula	Glucerna formula	consuming 200 kcal of Glucerna shake for breakfast
Oatmeal breakfast	Oatmeal breakfast	consuming 200 kcal of plain cooked oatmeal for breakfast
Oatmeal breakfast	Glucerna formula	consuming 200 kcal of plain cooked oatmeal for breakfast
Oatmeal breakfast	Ultra Glucose Control formula	consuming 200 kcal of plain cooked oatmeal for breakfast
Glucerna formula	Ultra Glucose Control formula	consuming 200 kcal of Glucerna shake for breakfast
Ultra Glucose Control formula	Glucerna formula	consuming 200 kcal of Ultra Glucose Control shake for breakfast

Primary Outcome Measures

Name	Time	Method
Glucose area under the curve 0-240 minutes	240 minutes