Calculation of the dose of the medicine, phenylephrine, for correcting fall in blood pressure during caesarean delivery under spinal anaesthesia in patients with preeclampsia

Phase 4

Completed

• Conditions: Health Condition 1: O82- Encounter for cesarean delivery without indicationHealth Condition 2: O149- Unspecified pre-eclampsia

• Registration Number: CTRI/2021/02/031073
• Lead Sponsor: niversity College of Medical Sciences and Guru Teg Bahadur Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-06-07
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

For Preeclamptic group

1. Preeclamptic females with singleton pregnancy undergoing caesarean section under spinal anaesthesia

2. Preeclampsia diagnosed as BP > 140/90 mmHg on two or more occasions at least 4 hrs apart and proteinuria > 300 mg/ 24 hrs or > 1+ dipstick test

For Normotensive group

Healthy females with term uncomplicated singleton pregnancy undergoing elective caesarean section under spinal anaesthesia

Exclusion Criteria

Maternal complications other than preeclampsia e.g. chronic hypertension, other cardiovascular disease, cerebrovascular disease

2. Multiple gestation

3. Known fetal abnormality

4. Patients with absolute or relative contra-indications for spinal anaesthesia e.g. infection in lumbar area, coagulation abnormalities, platelet count < 75 x 109/l, autonomic neuropathy, spinal deformities, other neurological diseases.

5. Severe fetal distress or other conditions requiring immediate induction of general anaesthesia

6. Maternal baseline systolic blood pressure less than 100 mmHg

Study & Design

• Study Type: Interventional
• Study Design: Not specified