CTRI/2021/02/031073CompletedPhase 4
Calculation of effective dose of phenylephrine bolus for treatment of post-spinal hypotension in preeclamptic patients undergoing caesarean section- A non randomised controlled trial
niversity College of Medical Sciences and Guru Teg Bahadur Hospital0 sites100 target enrollmentStarted: TBDLast updated:
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Enrollment
- 100
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •For Preeclamptic group
- •1. Preeclamptic females with singleton pregnancy undergoing caesarean section under spinal anaesthesia
- •2. Preeclampsia diagnosed as BP > 140/90 mmHg on two or more occasions at least 4 hrs apart and proteinuria > 300 mg/ 24 hrs or > 1+ dipstick test
- •For Normotensive group
- •Healthy females with term uncomplicated singleton pregnancy undergoing elective caesarean section under spinal anaesthesia
Exclusion Criteria
- •Maternal complications other than preeclampsia e.g. chronic hypertension, other cardiovascular disease, cerebrovascular disease
- •2. Multiple gestation
- •3. Known fetal abnormality
- •4. Patients with absolute or relative contra-indications for spinal anaesthesia e.g. infection in lumbar area, coagulation abnormalities, platelet count < 75 x 109/l, autonomic neuropathy, spinal deformities, other neurological diseases.
- •5. Severe fetal distress or other conditions requiring immediate induction of general anaesthesia
- •6. Maternal baseline systolic blood pressure less than 100 mmHg
Investigators
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