Comparison the effect of pretreatment with lbuprofen, Indomethacin, and placebo on the success of inferior alveolar nerve block for teeth with irreversible pulpitis
- Conditions
- Teeth with irreversible pulpitis.Diseases of pulp and periapical tissues
- Registration Number
- IRCT138803192016N1
- Lead Sponsor
- Oral and Dental Resrach Center and Vice-Chancellor for Research, Kerman University of Medical Scienc
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 150
Age more than 18 years, no contraindications to taking either Ibuprofen or Indomethacin (history of any allergic reaction to aspirin, NSAIDS, or Lidocaine with Epinephrine, nasal polyp, history of peptic ulcers or GI bleeding, pregnancy and lactation, renal or hepatic disease), no history of GI disorders or ulcer, having no serious systemic disease.
Exclusion criteria: no response to cold test, having sensitivity to percussion and palpation, having radiographic changes such as PDL widening, lack of vital pulp in coronal pulp chamber access cavity preparation, teeth with evidence of crack in their crown, having advanced periodontal disease, taking narcotic drugs or analgesic drugs in recent 12 hours before treatment.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response to cold test. Timepoint: 1 hour after taking drug. Method of measurement: using cold spray.
- Secondary Outcome Measures
Name Time Method Pain. Timepoint: After injection of local anesthesia and during treatment. Method of measurement: using visual analoug scale (VAS).