Comparison the effect of pretreatment with lbuprofen, Indomethacin, and placebo on postoperative pain of mandibular molars with irreversible pulpitis.
- Conditions
- Postoperative pain.Diseases of pulp and periapical tissues
- Registration Number
- IRCT138811082016N3
- Lead Sponsor
- Oral and Dental Research Center and Vice-Chancellor for Research of Kerman University of Medical Sci
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 150
Age more than 18 years, no contraindications to taking either Ibuprofen or Indomethacin (history of any allergic reaction to aspirin, NSAIDS, or Lidocaine with Epinephrine, nasal polyp, history of peptic ulcers or GI bleeding, pregnancy and lactation, renal or hepatic disease), no history of GI disorders or ulcer, having no serious systemic disease.
Exclusion criteria: no response to cold test, having sensitivity to percussion and palpation, having radiographic changes such as PDL widening, lack of vital pulp in coronal pulp chamber access cavity preparation, the teeth with large restoration, teeth with evidence of crack in their crown, presence of periapical radiolucency, internal resorption or calcification, and also taking narcotic drugs or analgesic drugs in recent 12 hours before treatment.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative pain. Timepoint: 6, 12, 24, and 48 hours after the procedure. Method of measurement: Using Heft-Parker -Visual Analogue Scale (VAS).
- Secondary Outcome Measures
Name Time Method