Effects of PEP on IC During IT in Patients With COPD
- Conditions
- Chronic Obstructive Pulmonary Disease
- Registration Number
- NCT03657082
- Lead Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Brief Summary
This study will investigate the effects of positive expiratory pressure (PEP) on hyperinflation in patients with chronic obstructive pulmonary disease (COPD). Inspiratory capacity (IC) is the primary outcome
- Detailed Description
This is a cross-over intervention assessing the effect of PEP on IC and dyspnea in patients with COPD performing an interval training (IT) session.
IC will be measured before, during and immediately after the IT session. Each participant will receive perform IT sessions including either the use of a PEP of 10 cmH2O or a PEP of 1 cmH2O. The effects on IC and dyspnea on both PEP levels will be assessed.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 1
- Stable COPD since 1 month at least
- Able to understand the instructions
- COPD with a forced expiratory volume at one second > 80% of predicted values
- In exacerbation
- Orthopedic of neurological condition likely to interfere with the experimentation
- Contraindication to perform exercise
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Change in inspiratory capacity 20 minutes Evolution of inspiratory capacity while performing the interval training session
- Secondary Outcome Measures
Name Time Method Change in Borg scale 20 minutes Evolution of dyspnea while performing the interval training session
Trial Locations
- Locations (1)
Cliniques universitaires Saint-Luc
🇧🇪Brussels, Belgium
Cliniques universitaires Saint-Luc🇧🇪Brussels, Belgium