Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects

Phase 4

Recruiting

• Conditions: Intrabony Periodontal Defect

• Registration Number: NCT06048042
• Lead Sponsor: Cairo University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-9-9
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Inclusion Criteria:<br><br> - Patient-related criteria:<br><br> - Motivated patient 18 years of age or order.<br><br> - Patient consulting in the outpatient clinic.<br><br> - Patient ready to perform oral hygiene instructions.<br><br> - Provide informed consent.<br><br> - Accepts the 6 months follow-up period.<br><br> - Teeth related criteria:<br><br> - Tooth with two or three-walled intra-bony defect, probing depth = 5mm with<br> intra osseous defect = 3mm.<br><br> - Mature permanent tooth.<br><br> - Unrestorable tooth or fractured tooth beyond restoration, impacted third molar<br> or supernumerary tooth to be extracted and used as whole tooth graft inside the<br> intrabony defect.<br><br>Exclusion Criteria:<br><br> - Patient-related criteria:<br><br> - Medically compromised patients.<br><br> - Pregnant women.<br><br> - Uncooperative patients.<br><br> - Smokers.<br><br> - Systemic diseases that may compromise healing or bone metabolism (e.g diabetes,<br> hyperthyroidism).<br><br> - Failure to maintain good oral hygiene.<br><br> - Teeth related criteria:<br><br> - Teeth with supra-bony defects.<br><br> - Teeth with grade III mobility.<br><br> - Teeth having interproximal craters, grade III furcation involvement, and grade<br> III mobility.<br><br> - Presence of caries or overhanging restorations.<br><br> - Presence of peri-apical injuries.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical attachment level (CAL) gain change from baseline to 6 months.

Secondary Outcome Measures

Name	Time	Method
Linear bone fill change from baseline to 6 months;Gingival index (GI) change from baseline to 6 months;Plaque index (PI) change from baseline to 6 months;Probing pocket depth (PPD) change from baseline to 6 months;Gingival recession (GR) change from baseline to 6 months;Bleeding on probing (BoP) change from baseline to 6 months;Postoperative Pain;Patient satisfaction