The effects of daily neuromuscular electrical stimulation during short term one-legged knee immobilization on muscle mass in healthy young me

Completed

• Conditions: muscle metabolism; disuse atrophy; 10037008; 10028302

• Registration Number: NL-OMON37432
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

- Male
- Aged between from 18-35 years
- BMI above 18.5 and below 30 kg/m2

Exclusion Criteria

- Any family history of thromboses
- All co-morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. arthritis, spasticity/rigidity, all neurological disorders and paralysis).
- Diagnosed impaired renal or liver function
- Myocardial infarction within the last 3 years
- Use of anti-coagulants

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary: Quadriceps CSA</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>quadriceps lean mass, type I and II muscle fiber CSA and SC content, muscle<br /><br>strength.</p><br>