Development of a Decision-making Aid for Referring Severe Kidney Injury Patients for Nephrology Consultations

Centre Hospitalier Universitaire de Nīmes1 site in 1 country319 target enrollmentAugust 20, 2016

ConditionsChronic Kidney Diseases Acute Kidney Injury

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Chronic Kidney Diseases
Sponsor: Centre Hospitalier Universitaire de Nīmes
Enrollment: 319
Locations: 1
Primary Endpoint: Develop a prognostic score of progression to chronic kidney disease at 6 months in patients requiring hospitalization for dialysis for acute kidney injury to identify those who would benefit from consultation with a nephrologist
Status: Completed
Last Updated: 5 months ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Acute kidney injury is a frequent and growing complication associated with a risk of progressing into a chronic kidney disease. Recent guidelines have recommended systematic consultations with a nephrologist 3-6 months following hospitalization. Risk factors of developing chronic kidney disease between hospital visits are understudied.

Registry

clinicaltrials.gov

Start Date

August 20, 2016

End Date

June 15, 2018

Last Updated

5 months ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Centre Hospitalier Universitaire de Nīmes

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Age \>18 years
•Suffering from acute kidney injury treated with dialysis
•hospitalized in a university center from August 2016 to December 2017 with severe AKI defined according to 2 of the 3 criterion definitions of KDIGO stage AKI: an increase in SCr above 354 μmol/Lor renal replacement therapy (RRT) indication, but not the 3-fold increase in SCr increase within 7 days with SCr below 354 μmol/L.
•The patient has been informed and does not oppose the study
•The patient is insured or the beneficiary of a health insurance policy

Exclusion Criteria

•The patients is under judicial protection or state guardianship
•Patient has chronic kidney disease(CKD) KDIGO stage 5
•It proves impossible to give the patient clear information
•patients living with kidney transplant
•plan dialysis for bilateral surgery nephrectomy
•patient refuse to participate and patients with no health insurance

Outcomes

Primary Outcomes

Develop a prognostic score of progression to chronic kidney disease at 6 months in patients requiring hospitalization for dialysis for acute kidney injury to identify those who would benefit from consultation with a nephrologist

Time Frame: 6 months

Secondary Outcomes

Identify new risk factors for progression to chronic kidney disease at 6 months post dialysis for acute kidney injury pre-hospitalization and during hospitalization and day of discharge(6 months)
Identify renal phenotype of patients with chronic kidney disease(6 months)
Evaluate mortality during hospital stay(1 months)
Evaluate mortality at medium-term(6 months)
Identify specific therapeutic interventions put into place during the 6 month consultation(6 months)