CTRI/2025/11/098096尚未招募不适用
To assess the effect of preoperative oral carbohydrate electrolyte drink on postoperative insulin resistance in diabetic patients undergoing gastro-intestinal surgery : a randomized controlled study
Dr. swati singh1 个研究点 分布在 1 个国家目标入组 114 人开始时间: 2026年1月1日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- The primary outcome is insulin resistance assessed
研究概览
简要总结
Aim of this study is to investigate whether shortening the preoperative
fast using a solution containing carbohydrates can alter the acute-phase response
and clinical outcomes of elective major operations of the digestive tract by assessing insulin resistance
by HOMA-IR on postoperative day 1 and also assessing Perioperative glycemia, length of stay, fasting blood glucose, fasting insulin,
insulin secretion index, insulin sensitivity index, intraoperative and post
operative blood glucose upto 24 h post-surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having Diabetes Mellitus Type 2 undergoing elective gastric surgery, colorectal surgery (CRS) with FBS less than 200 mg/dl and HbA1c less than 7 will be included.
- •Expected postoperative hospital stay of more than 72 h.
排除标准
- •patients undergoing emergency surgery or secondary surgery
- •patients with inability to receive enteral nutrition
- •patients with comorbidities to ensure the safety of the trial and minimize the occurrence of adverse events
- •patients with mental disorders, alcohol addiction, or drug abuse history
- •lactating and pregnant women
- •patients with allergy to maltodextrin and various drugs.
结局指标
主要结局
The primary outcome is insulin resistance assessed
时间窗: 24 hour after surgery
by HOMA-IR on postoperative day 1.
时间窗: 24 hour after surgery
次要结局
- The secondary outcomes will be(Perioperative glycemia, length of stay, fasting blood glucose, fasting insulin,)
研究者
Dr Swati Singh
Indira gandhi institute of medical sciences, patna
研究点 (1)
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