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Comparing the effects of Atorvastatin and Rosuvastatin in preventing acute kidney injury due to contrast media

Not Applicable
Conditions
Other and unspecified drugs and medicament
Contrast Induced Nephropathy.
Registration Number
IRCT2017101236737N1
Lead Sponsor
Vice chancellor for research, Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
200
Inclusion Criteria

occurrence of first episode of ST elevation Myocardial Infarction (STEMI); performing primary per-cutaneous coronary intervention for patients.
Exclusion criteria: patients under-dialysis; acute kidney injury before angiography; cardiogenic shock; consumption of drugs like N-acetyl cysteine, vitamin C, consumption of venous contrast for other cause, manitol, diuretics, Theophylline and Dopamin in recent two weeks before PCI; having intra-aortic balloon pump; patients with previous cardiac surgery; patients who were candidate for CABG after angioplasty; patients who received G2b3a drugs during PPCI

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
evel of serum creatinine. Timepoint: 24 hours after intervention and 72 hours after intervention. Method of measurement: mg/ deciliter.
Secondary Outcome Measures
NameTimeMethod
Glumerolar filtration rate. Timepoint: 24hours after intervention and 72hours after intervention. Method of measurement: ml/min/1.73 m2.
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