Effects of atorvastatin and rosuvastatin on prevention of atrial fibrillatio
Phase 2
Recruiting
- Conditions
- Atrial fibrillation post coronary artery bypass graft.Paroxysmal atrial fibrillationI48.0
- Registration Number
- IRCT20191109045384N1
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
The preoperative EKG of the patient must have sinus rhythm
For the study, the patient must have satisfaction
The patient must be a candidate for elective surgery
The CABG surgery of the patient should be on pump
Exclusion Criteria
Urgent CABG surgery
Previous cardiac surgery
Cardiac surgery except CABG
Left ventricular ejection fraction less than or equal to 25%
Diameter of left atrium more than 6 cm in echocardiography
Need to inotropic agents after surgery
Being dependent on pace maker after surgery
The patient's rhythm shouldn't be sinus.
Hyperthyroidism
Aortic and mitral valves disorder more than moderate
Renal failure
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence rate of atrial fibrillation post coronary artery bypass graft. Timepoint: Holter monitoring for 72 hours and daily ECG for one week and if it continues after one week, daily ECG will be taken until discharge.(up to 1 month). Method of measurement: Holter momitor and ECG devices.
- Secondary Outcome Measures
Name Time Method Incidence of diabetes and myopathy as possible complications of rosuvastatin. Timepoint: Fasting blood glucose and creatine phosphokinase measurement and clinical examination at the end of the first week and then at the end of the first month and then six months later. Method of measurement: Clinical examination and testing of fasting blood glucose and creatine phosphokinase.