Effects of Exercise-intensity on Physiological Adaptations in Overweight and Obese

Not Applicable

Completed

• Conditions: Obesity; Overweight
• Interventions: Behavioral: Long distanse moderate training; Behavioral: Short interval training; Behavioral: Long interval training

• Registration Number: NCT01453972
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The main purpose of our study is to examine the physiological adaptations in oxygen transport chain for high-intensity exercise and moderate exercise in overweight and obese humans. The main goals are:

1. To investigate the most effective short-and long-interval training in terms of VO2max, pulmonary diffusion, cardiac output, endothelial function and mitochondrial function.

2. How these physiological adaptations affect the aerobic endurance and performance, and how this training can reduce the risk of cardiovascular diseases related to overweight and obesity.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-10
• Study First Submitted: 2011-10-10
• Study First Submitted QC: 2011-10-13
• Study First Posted: 2011-10-18
• Primary Completion: 2012-02
• Study Completion: 2012-12
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-01
• Last Update Posted: 2016-08-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• BMI > 25

Exclusion Criteria

• Exclusion criteria will be cardiovascular disease or another disease that is not consistent with high physical activity. Subjects should not have exercised regularly before the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Long distanse moderate training	Long distanse moderate training	40 minutes moderate treadmill running
Short interval training	Short interval training	10x1min interval treadmill running
Long interval training	Long interval training	4x4min interval treadmill running

Primary Outcome Measures

Name	Time	Method
Maximal oxygen uptake	6 weeks	Change in maximal oxygen uptake will be measured after six weeks of various exercise training and related to changes in blood volume, cardiac function, endothelial function and mitochondrial function.

Trial Locations

Locations (1)

Medical Faculty, Norwegian University of Science and Technology; 🇳🇴 Trondheim, Sør-Trøndelag, Norway