Prevention for Positives: An RCT Among Vietnamese HIV-positive IDU
- Conditions
- HIV
- Interventions
- Behavioral: Structural levelBehavioral: Individual level standard of careBehavioral: Individual levelBehavioral: Structural level standard of care
- Registration Number
- NCT01689545
- Lead Sponsor
- Johns Hopkins Bloomberg School of Public Health
- Brief Summary
The purpose of this study is to determine whether a combined individual and structural level stigma reduction intervention is effective in reducing high risk injecting and sexual behaviors among HIV positive injecting drug users.
- Detailed Description
This study is a randomized controlled trial among HIV-positive injecting drug users (IDUs) to reduce high risk injecting and sexual behaviors in Thai Nguyen, Vietnam. We will be conducting this study in collaboration with the Thai Nguyen Centre for Preventive Medicine (CPM). We will compare standard HIV voluntary counseling and testing (VCT) to an intervention that adds a continuum of psychosocial support for HIV-positive IDUs. The intervention consists of a two-tiered approach that addresses structural and individual level barriers to risk reduction: 1) The structural level of the intervention consists of community-based programs and targets HIV stigma that is a primary obstacle to risk reduction for HIV-positive individuals; 2) The individual level of the intervention consists of 2 HIV posttest counseling sessions and 2 skill-building support groups for HIV-positive IDUs. Our research questions for the overall project are:
1. What is the impact of perceived HIV-related stigma on disclosure, social support, and coping among IDUs?
2. What roles do disclosure, social support, and coping play in facilitating the reduction of HIV-risk behaviors
3. Are combined individual and structural level interventions more effective in reducing injecting and sexual behaviors among HIV-positive IDUs than individual or structural interventions alone and more effective than the standard HIV VCT?
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 2175
- laboratory confirmed HIV positive diagnosis
- able and wiling to bring an injecting network member for screening
- injected drugs in previous 6 months
- planned residence in Thai Nguyen for next 24 months
- unwilling to provide locator information
- unable to participate in group counseling sessions due to psychological disturbance, cognitive impairment or threatening behavior
- currently participating in other HIV or drug use intervention activities
Network member participant
Inclusion Criteria:
- laboratory confirmed HIV negative diagnosis
- injected or shared drug paraphernalia in past 6 months
- interacts at least once a week with index participant
Exclusion Criteria:
- unwilling to provide locator information
- having psychological or cognitive impairment
- currently participating in other HIV intervention
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Arm && Interventions
Group Intervention Description Structural level Structural level - Standard of Care Individual level standard of care - Structural level Individual level standard of care - Individual level Individual level - Combined individual & structural level Individual level - Standard of Care Structural level standard of care - Individual level Structural level standard of care - Combined individual & structural level Structural level -
- Primary Outcome Measures
Name Time Method HIV injecting risk behavior 2 years Change in self-reported use of new injecting equipment
HIV sexual risk behavior 2 years Change in self-reported condom use during sexual intercourse
- Secondary Outcome Measures
Name Time Method HIV incidence 2 years Change in HIV incidence among network members
Trial Locations
- Locations (1)
Center for Preventive Medicine
🇻🇳Thai Nguyen, Vietnam