Correlation between High Platelet Reactivity with Loading Dose of Prasugrel and Clinical Outcome in the Patients with Acute Coronary Syndrome
Not Applicable
Recruiting
- Conditions
- acute coronary syndrome
- Registration Number
- JPRN-UMIN000029729
- Lead Sponsor
- Okayama City Hospital
- Brief Summary
eft ventricular remodeling (LVR) in the chronic phase was found in 34 patients (18.7%) whose platelet reactivity was significantly higher than those without LVR (260PRU vs. 213PRU, P=0.001). Left ventricular end-diastole volume index (LVEDVI) significantly decreased at the chronic phase in patients without high platelet reactivity (HPR), but not in patients with HPR. Multivariate logistic analysis showed that HPR was an independent predictor of LVR (OR 4.13, 95%CI 1.85-9.79).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 182
Inclusion Criteria
Not provided
Exclusion Criteria
(a) patients wiht bleeding tendency (b) patients with allagy against thienopyridine drugs (c)patients who are not suitable for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method composite of all death, myocardial death, myocardial infarction, stroke, ventricular arrhythmia needing defibrillation, cardiac rupture and serious hemorrhage within 30 days of onset
- Secondary Outcome Measures
Name Time Method composite of all death, myocardial death, myocardial infarction, stroke, heart-failure hospitalization, target lesion revascularization and serious hemorrhage within one year of onset