Functional Impairment of Reading Ability in Dry Eye Patients and Effects of Sustained Reading on the Ocular Surface

Johns Hopkins University1 site in 1 country200 target enrollmentApril 2013

ConditionsDry Eye Syndromes

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Dry Eye Syndromes
Sponsor: Johns Hopkins University
Enrollment: 200
Locations: 1
Primary Endpoint: Sustained Silent Reading Speed
Status: Completed
Last Updated: 8 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

To assess the reading function impairment in patients with dry eye and to assess the effects of reading on the ocular surface.

Detailed Description

This study is being done to understand how reading is affected in people with dry eye in comparison with healthy controls and what effect reading has on the ocular surface in patients with dry eye.

Registry

clinicaltrials.gov

Start Date

April 2013

End Date

November 2015

Last Updated

8 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Johns Hopkins University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•age of 50 or greater,
•literacy in English language,
•ability to give informed consent

Exclusion Criteria

•binocular vision below 20/25,
•any ocular surgery within the last 3 months,
•mental issues,
•illiteracy,
•language problems which might possibly interfere with reading ability,
•history of taking or current use of topical prescription anti-inflammatory eye drops (including, cyclosporine and steroids as well as any glaucoma eye drops).

Outcomes

Primary Outcomes

Sustained Silent Reading Speed

Time Frame: 30 minutes

Secondary Outcomes

Change in Total Ocular Staining Score (OSS)(Before and after 30 minutes reading)
Change in Tear Osmolarity(Before and after 30 minutes reading)
Change in Visual Acuity(30 minutes)
Cytokines(Tear samples were collected on the day of the exam. The samples were frozen to be assayed upon completion of the study.)