Prevalence of SARS -Cov2 Carriage in Asymptomatic and Mildly-symptomatic Children, a Cross-sectional, Prospective, Multicentre, Observational Study in Primary Care-Part 2 After the Lifting of the Lockdown
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Proportion of asymptomatic children or children with mild respiratory symptoms
研究概览
简要总结
France and in particular the paris area was one of the countries most affected by the pandemic Covid19.
School closures and a generalized lockdown of the population were instituted in France from 17 March 2020 to 10 May 2020. Schools and nurseries have reopened partially since 11 May 2020. From 2 June, this reopening is more widespread. By combining the search for SARS-Cov2 viruses by PCR and micro-method serology we will be able to evaluate both the infection at a given time and also older contact with SARS-CoV2.
The temporal knowledge of the prevalence of SARS-Cov2 carriage and the serological status (IgM and IgG) after return to the community are crucial information to evaluate the speed of spread of the virus in children. This is the objective of COVILLE2, phase 2 of the COVILLE study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 15 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Birth to 15 years old
- •taking over the community (kindergarten, school, college, holiday centre, etc.) for at least 1 week
排除标准
- •refusal to participate
结局指标
主要结局
Proportion of asymptomatic children or children with mild respiratory symptoms
时间窗: At inclusion
Proportion of asymptomatic children or children with mild respiratory symptoms (mildly-symptomatic children) with a positive SARS-Cov2 Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) on rhino pharyngeal swab or/and IgM/IgG positive serology in Paris area
次要结局
- Cov2-SARS cases by age(At inclusion)
- Viral load(At inclusion)
- Cov2-SARS cases by symptoms(At inclusion)
- Presence of anti-SARS-CoV-2 antibodies (IgM and IgG) by the rapid serological test(At inclusion)