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Clinical Trials/DRKS00022202
DRKS00022202
Completed
N/A

Protective Variable Controlled Ventilation during One Lung Anesthesia (PROVALUNG) – A Randomized Controlled Trial - PROVALUNG

Technische Universität Dresden0 sites78 target enrollmentJune 16, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Intraoperative one-lung ventilation
Sponsor
Technische Universität Dresden
Enrollment
78
Status
Completed
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
June 16, 2020
End Date
July 24, 2022
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Patients with planned thoracic surgery (open or video\-assisted) under one\-lung ventilation using a double lumen tube and invasive monitoring of arterial blood pressure
  • \- ASA \= 3
  • \- Planned duration of intervention \> 30 min
  • \- Age \= 18
  • \- Weight \> 40 kg
  • \- Written consent of the participating person

Exclusion Criteria

  • \- COPD GOLD grade 3 and 4
  • \- Untreated asthma
  • \- Lung separation using a method other than DLT (e.g. difficult airway, tracheostomy)
  • \- Contraindications against total intravenous anaesthesia
  • \- History of hypersensitivity/allergy to one of the medications to be used or their ingredients or to medication with a similar chemical structure
  • \- Participation of the patient in another clinical trial within the last 4 weeks before inclusion
  • \- Addictions or other illnesses which do not allow the person concerned to assess the nature and extent of the clinical trial and its possible consequences
  • \- Pregnant or breastfeeding women
  • \- Women of childbearing age, except women who meet the following criteria:
  • \> Post\-menopausal (12 months natural amenorrhoea or 6 months amenorrhoea with serum FSH \> 40 mlU/ml)

Outcomes

Primary Outcomes

Not specified

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