Protective Flow Controlled Ventilation during One Lung Anesthesia (PROFLONE) – A Randomized Controlled Trial

Technische Universität Dresden0 个研究点目标入组 78 人开始时间: 2020年6月16日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Patients with planned thoracic surgery (open or video-assisted) under one-lung ventilation using a double lumen tube and invasive monitoring of arterial blood pressure
•- ASA = 3
•- Planned duration of intervention > 30 min
•- Age = 18
•- Weight > 40 kg
•- Written consent of the participating person

•- COPD GOLD grade 3 and 4
•- Untreated asthma
•- Lung separation using a method other than DLT (e.g. difficult airway, tracheostomy)
•- Contraindications against total intravenous anaesthesia
•- History of hypersensitivity/allergy to one of the medications to be used or their ingredients or to medication with a similar chemical structure
•- Participation of the patient in another clinical trial within the last 4 weeks before inclusion
•- Addictions or other illnesses which do not allow the person concerned to assess the nature and extent of the clinical trial and its possible consequences
•- Pregnant or breastfeeding women
•- Women of childbearing age, except women who meet the following criteria:
•> Post-menopausal (12 months natural amenorrhoea or 6 months amenorrhoea with serum FSH > 40 mlU/ml)
•> Postoperative (6 weeks after bilateral ovarectomy with or without hysterectomy)
•> Regular and correct use of a contraceptive method with a failure rate < 1% per year (e.g. implants, depot injections, oral contraceptives, intrauterine device - IUD).

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