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Clinical Trials/NL-OMON36788
NL-OMON36788
Completed
Not Applicable

Pressure support ventilation and NAVA during noninvasive ventilation in acute respiratory failure: a pilot study - PSV and NAVA during noninvasive ventilation

niversitair Medisch Centrum Sint Radboud0 sites12 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
niversitair Medisch Centrum Sint Radboud
Enrollment
12
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
niversitair Medisch Centrum Sint Radboud

Eligibility Criteria

Inclusion Criteria

  • \* Acute respiratory failure requiring noninvasive ventilatory support in ICU.
  • \* COPD (past medical history)
  • \* Able to adequately oxygenate and ventilate without support for ± 5 minutes (necessary for changing the interface).
  • \* Age \> 18 years
  • \* Mentally competent

Exclusion Criteria

  • \* Severe hypoxemic failure (Pa,o2 \< 8\.0 kPa with nonrebreathing mask) at time of inclusion
  • \* Planned endotracheal intubation
  • \* Hemodynamic instability requiring high dose vasopressors (\>0\.5 ug/kg/min)
  • \* Contraindication for insertion of nasogastric tube (recent esophageal, facial or cranial trauma or surgery. espohageal varices, recent (\< 4 weeks) upper gastrointestinal bleeding)
  • \* Severe agitation
  • \* Myopathy before ICU admission (including Steinert disease, Duchenne muscular dystrophy)
  • \* Severely decreased consciousness (GCS \< 11\)
  • \* Tracheostomy
  • \* Inability to obtain informed consent.
  • \* Nasogastric tube in situ

Outcomes

Primary Outcomes

Not specified

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