TCTR20191217002招募中未知
The effect of soy milk on levothyroxine absorption
Faculty of Medicine Ramathibodi Hospital, Mahidol University0 个研究点目标入组 10 人开始时间: 2019年12月17日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 45 Years（—）
- 性别
- All
入选标准
- •1. Healthy volunteers
- •2. Aged 18-45 years
- •3. Written informed consent by volunteer
排除标准
- •1. Adults with recent acute illness, cardiovascular disease/abnormal electrocardiogram, renal insufficiency (serum creatinine >1.5 mg/dL), abnormal liver function (AST and/or ALT > 3 times of upper normal limit)
- •2. Use of certain medications that interfere with levothyroxine absorption such as iron, calcium, proton pump inhibitor, sucralfate, aluminium hydroxide, cholestyramine; affect with levothyroxine metabolism such as phenytoin, carbamazepine, phenobarbital, rifampicin, tyrosine kinase inhibitor
- •3. Use of certain medications that alter thyroid hormone levels such as amiodaraone, lithium, interfereon-alpha, alemtuzumab, glucocorticoid, somatostatin
- •4. Use of certain medications that affect with thyroxine-binding globulin such as estrogen, raloxifene, tamoxifen, mitotane, fluorouracil, methadone, heroin, androgen, nicotinic acid
- •5. Adults who had intestinal absorption problem or history of gastric/intestinal surgery
- •6. Adults with allergy to soy and/or levothyroxine
- •7. Pregnant women/lactating women
- •8. Adults who has abnormal TSH concentrations
- •9. Denied to participate in the study
研究者
相似试验
已完成
不适用
Absorption of levothyroxine with breakfast in healthy womeISRCTN12149022IBSA Institut Biochimique SA40
已完成
2 期
Effect of soymilk on cardiovascular risk factorsObesity and overweight.Obesity due to excess caloriesIRCT201107052839N3Tehran Univercity Of Medical Sciences, Isfahan Univercity Of Medical Sciences30
已完成
不适用
Effect of probiotic supplementation on diabetic nephropathyDiabetic nephropathy.Glomerular disorders in diabetes mellitusE11.21IRCT201601027479N2Isfahan University of Medical Sciences40
招募中
不适用
Effect of soy milk consumption on non-alcoholic fatty liver disease.on-alcoholic fatty liver disease.Fatty (change of) liver, not elsewhere classifiedIRCT201701162709N40Vice Chancellor for Research, Iran University of Medical Sciences70
已完成
不适用
The effects of soy milk consumption on gut microbium community, inflammatory markers, quality of life, symptoms and disease severity in patients with colitits ulcerativecolitis ulcerative.Ulcerative colitis, unspecifiedIRCT20181205041859N1Tehran University of Medical Sciences30