Health Promotion and Management for Hepatitis B Carriers

Not Applicable

• Conditions: Chronic Hepatitis B
• Interventions: Behavioral: standardized exercise program and dietary counseling

• Registration Number: NCT01065363
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The investigators propose a project of preventive medicine with concern of local context in Taiwan. The target population includes all staff and faculty members, students, and alumni of a university in Northern Taiwan, with chronic hepatitis B infection. The intervention of this project includes standardized lectures, sports courses, nutrition courses, and an information platform. The investigators will evaluate the efficacy after the intervention, like the reduction of hepatitis B viral load and the associated anthropometric parameters. The results of this project will be initially served as a pilot study for this cohort, and applicated as a promising basis for health promotion.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-08
• Status Verified: 2010-02
• Study First Submitted: 2010-02-08
• Study First Submitted QC: 2010-02-08
• Last Update Submitted: 2010-02-08
• Study First Posted: 2010-02-09
• Last Update Posted: 2010-02-09
• Primary Completion: 2010-07
• Study Completion: 2010-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

• Participants were recruited from students, alumni, faculty and staff members with chronic HBV infection (positive HBsAg serostatus ≥6 months) in a university of northern Taiwan from August 1, 2009 to July 01, 2010. Only participants aged 18 and older were included.

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Exclusion Criteria

• Excluded were:

  • (a) those who had been diagnosed as chronic liver diseases like chronic hepatitis C infection (Anti-HCV (+)), autoimmune hepatitis, Wilson disease, alcoholic liver diseases, drug-related hepatitis, decompensated liver diseases, cirrhosis, or malignant hepatic tumors;

• (b) those who had undergone liver transplantation or major operations for liver except cholecystectomy;

• (c) men who consumed more than 30 gram of alcohol per week or women who consumed more than 20 gram of alcohol per week;

• (d) women who were pregnant;

• (e) those who had current medications for any types of chronic diseases except for hyperglycemia, elevated blood pressure, or dyslipidemia within six months.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lifestyle conseling	standardized exercise program and dietary counseling	-

Primary Outcome Measures

Name	Time	Method
Reduction of relative serum HBV DNA levels	three months

Secondary Outcome Measures

Name	Time	Method
anthropometric index	three months

Trial Locations

Locations (1)

National Taiwan University Health Center; 🇨🇳 Taipei, Taiwan