Effect of the National Taiwan University Hospital Elder Life Program
Overview
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 377
- Locations
- 1
- Primary Endpoint
- Frailty rates and transition between frailty states
Overview
Brief Summary
The aim is to replicate, develop, and pilot test a model of care for the prevention and management of functional decline of older patients during hospitalization.
Detailed Description
to develop an intervention protocol that achieves clinical development objectives in a scientifically rigorous and time efficient manner.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 65 Years to — (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age 65 year and older
- •Length of Stay is over 6 days
- •Able to communicate verbally or in writing
Exclusion Criteria
- •Mechanism ventilation
- •Aphasia, if communication ability is severely impaired
- •Terminal condition with comfort care only, death imminent
- •Combative or dangerous behavior
- •Severe psychotic disorder that prevents patient from participating in interventions
- •Severe dementia (e.g. unable to communicate; MMSE=0). For patients with severe impairment (e.g. MMSE\<10), decision to enroll will be made on a case-by-case basis depending on their ability to participate in intervention.
- •Respiratory isolation (e.g. tuberculosis). Patients on contact isolation (e.g. vancomycin-resistant enterococcus) or droplet precautions will be enrolled.
- •Discharge firmly anticipated within 6 days of admission. Enroll if discharge date unsure
- •Refusal by patient or family member.
- •Others. Reason to be well documented.
Outcomes
Primary Outcomes
Frailty rates and transition between frailty states
Time Frame: through study completion, an average of 3 months
Changes from Baseline Frailty rates at 6 weeks after discharge
Postoperative delirium incidence rate [Confusion Assessment Method (CAM)]
Time Frame: through study completion, an average of 3 months
Record the incidence of postoperative delirium developing during hospitalization after surgery
Functional status:Barthel Index.
Time Frame: through study completion, an average of 3 months
Changes from Baseline Barthel Index (BI) scores at 6 weeks after discharge
Mini-Nutritional Assessment scores (MNA)
Time Frame: through study completion, an average of 3 months
Changes from Baseline Mini-Nutritional Assessment (MNA) scores at 6 weeks after discharge
Mini Mental State Examination scores (MMSE)
Time Frame: through study completion, an average of 3 months
Changes from Baseline Mini Mental State Examination (MMSE) scores at 6 weeks after discharge
Postoperative bowel dysmotility
Time Frame: through study completion, an average of 3 months
Record the incidence of postoperative bowel dysmotility developing during hospitalization after surgery
Secondary Outcomes
- Body weight(through study completion, an average of 3 months)
- Grip strength(through study completion, an average of 3 months)
- Length of Hospital Stay (LOS)(through study completion, an average of 3 months)
- Oral health(through study completion, an average of 3 months)
- Executive function(through study completion, an average of 3 months)
- Geriatric Depressive Scale scores (GDS)(through study completion, an average of 3 months)