a Modified NTU-HELP Program
- Conditions
- Early Ambulation
- Interventions
- Behavioral: a modified NTU-HELP
- Registration Number
- NCT01045330
- Lead Sponsor
- National Taiwan University Hospital
- Brief Summary
The aim is to replicate, develop, and pilot test a model of care for the prevention and management of functional decline of older patients during hospitalization.
- Detailed Description
to develop an intervention protocol that achieves clinical development objectives in a scientifically rigorous and time efficient manner.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 377
- Age 65 year and older
- Length of Stay is over 6 days
- Able to communicate verbally or in writing
- Coma
- Mechanism ventilation
- Aphasia, if communication ability is severely impaired
- Terminal condition with comfort care only, death imminent
- Combative or dangerous behavior
- Severe psychotic disorder that prevents patient from participating in interventions
- Severe dementia (e.g. unable to communicate; MMSE=0). For patients with severe impairment (e.g. MMSE<10), decision to enroll will be made on a case-by-case basis depending on their ability to participate in intervention.
- Respiratory isolation (e.g. tuberculosis). Patients on contact isolation (e.g. vancomycin-resistant enterococcus) or droplet precautions will be enrolled.
- Discharge firmly anticipated within 6 days of admission. Enroll if discharge date unsure
- Refusal by patient or family member.
- Others. Reason to be well documented.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Experimental Group a modified NTU-HELP The intervention consisted of a daily inpatient care protocol on three core intervention protocols on top of hospital routine care.
- Primary Outcome Measures
Name Time Method Frailty rates and transition between frailty states through study completion, an average of 3 months Changes from Baseline Frailty rates at 6 weeks after discharge
Functional status:Barthel Index. through study completion, an average of 3 months Changes from Baseline Barthel Index (BI) scores at 6 weeks after discharge
Postoperative delirium incidence rate [Confusion Assessment Method (CAM)] through study completion, an average of 3 months Record the incidence of postoperative delirium developing during hospitalization after surgery
Mini-Nutritional Assessment scores (MNA) through study completion, an average of 3 months Changes from Baseline Mini-Nutritional Assessment (MNA) scores at 6 weeks after discharge
Mini Mental State Examination scores (MMSE) through study completion, an average of 3 months Changes from Baseline Mini Mental State Examination (MMSE) scores at 6 weeks after discharge
Postoperative bowel dysmotility through study completion, an average of 3 months Record the incidence of postoperative bowel dysmotility developing during hospitalization after surgery
- Secondary Outcome Measures
Name Time Method Length of Hospital Stay (LOS) through study completion, an average of 3 months Record the length of hospital stay for abdominal surgery
Body weight through study completion, an average of 3 months Changes from Baseline Body weight at 6 weeks after discharge
Grip strength through study completion, an average of 3 months Changes from Baseline Grip strength at 6 weeks after discharge
Oral health through study completion, an average of 3 months i.e., plaque index, screens of swallowing function
Executive function through study completion, an average of 3 months ie.e, color trail test
Geriatric Depressive Scale scores (GDS) through study completion, an average of 3 months Changes from Baseline Geriatric Depressive Scale scores (GDS) at 6 weeks after discharge
Trial Locations
- Locations (1)
National Taiwan Unversity Hospital
🇨🇳Taipei, Taiwan