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Clinical Trials/NCT01562509
NCT01562509
Unknown
Not Applicable

Improvement of Hospital Care for Patients With Non-Hodgkin's Lymphoma

Radboud University Medical Center1 site in 1 country418 target enrollmentOctober 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Non-Hodgkin Lymphoma
Sponsor
Radboud University Medical Center
Enrollment
418
Locations
1
Primary Endpoint
Change from baseline in adherence to quality indicators for NHL care
Last Updated
11 years ago

Overview

Brief Summary

The main objective of the proposed study is to assess the effectiveness, feasibility and costs of a tailored strategy (developed in accordance with the barriers found and current practice) to improve care for patients with non-Hodgkin's lymphomas (NHL), compared to a common strategy of 'audit & feedback'.

Detailed Description

In a previous study among 22 Dutch hospitals many gaps in the care for patients with non-Hodgkin's lymphomas (NHL) were found, compared to best evidence as described in guidelines. In a problem analysis study, barriers and facilitators for good quality of NHL-care were assessed and a tailored implementation strategy was developed, based on these findings. The proposed study aims at the effectiveness, feasibility and costs of this tailored strategy to improve quality of care for patients with an NHL in a clustered randomized controlled trial in 19 Dutch hospitals. Multilevel regression analyses will be performed to evaluate the effectiveness of both strategies. Exposure to and experiences with the strategy elements will be analysed descriptively. Regarding the costs, the two strategies are compared with a health care perspective. The input of resources will be assessed by collecting volumes of consumed resources and multiplying these by the price of each resource unit; the implementation process and consequently costs will be estimated by an Activity Based Costing (ABC) approach. The output will be determined by the level of adherence to the NHL quality indicators.

Registry
clinicaltrials.gov
Start Date
October 2012
End Date
December 2014
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Clinical diagnosis of non-Hodgkin lymphoma
  • Diagnosed in one of the participating hospitals
  • Able to read and understand Dutch

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Change from baseline in adherence to quality indicators for NHL care

Time Frame: baseline and 1 year

The effect of our interventions will be measured by means of adherence to quality indicators for optimal NHL care. The effects of the audit and feedback strategy (9 hospitals) versus the tailored strategy (9 hospitals) will be evaluated using previously developed quality indicators. These indicators for optimal NHL care were developed on the basis of evidence based guidelines, literature and opinions of clinicians about NHL care in a previous study and were validated.

Secondary Outcomes

  • Change from baseline in morbidity(baseline and 1 year)
  • Exposure to and experiences with the interventions(after 1 year)
  • Costs of the strategy and the changed care(after 1 year)
  • Differences between both groups in Patient Related Outcome Measures (PROMs)(after 1 year)

Study Sites (1)

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